Methemoglobinemia induced by topical anesthetic (benzocaine).

Linares, L A; Peretz, T Y; Chin, J · Radiother Oncol · 1990

case_report · Level V

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Abstract

Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and does not respond to oxygen. We describe a patient with esophageal carcinoma who developed severe methoglobinemia following application of benzocaine in spray for local anesthesia prior to intraluminal irradiation. Review of the literature is presented.

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