PopDrowser: the Population Drosophila Browser.

Ràmia, Miquel; Librado, Pablo; Casillas, Sònia; Rozas, Julio; Barbadilla, Antonio · Bioinformatics · 2012

basic_science · Level V

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Abstract

The completion of 168 genome sequences from a single population of Drosophila melanogaster provides a global view of genomic variation and an understanding of the evolutionary forces shaping the patterns of DNA polymorphism and divergence along the genome. We present the 'Population Drosophila Browser' (PopDrowser), a new genome browser specially designed for the automatic analysis and representation of genetic variation across the D. melanogaster genome sequence. PopDrowser allows estimating and visualizing the values of a number of DNA polymorphism and divergence summary statistics, linkage disequilibrium parameters and several neutrality tests. PopDrowser also allows performing custom analyses on-the-fly using user-selected parameters. PopDrowser is freely available from http://PopDrowser.uab.cat.

Medical subject headings