Brief reports: plasma ropivacaine concentrations after ultrasound-guided rectus sheath block in patients undergoing lower abdominal surgery.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 22184611.
- Also identified by DOI 10.1213/ANE.0b013e3182367a68.
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Abstract
A rectus sheath block can provide postoperative analgesia for midline incisions. However, information regarding the pharmacokinetics of local anesthetics used in this block is lacking. In this study, we detail the time course of ropivacaine concentrations after this block. Thirty-nine patients undergoing elective lower abdominal surgery were assigned to 3 groups receiving rectus sheath block with 20 mL of different concentrations of ropivacaine. Peak plasma concentrations were dose dependent, and there were no significant differences in the times to peak plasma concentrations. The present data also suggested a slower absorption kinetics profile for ropivacaine after rectus sheath block than other compartment blocks.
Medical subject headings
- Abdomen
- Amides
- Anesthetics, Local
- Nerve Block
- Postoperative Pain
- Ultrasonography, Interventional