Cellulose synthase interactive protein 1 (CSI1) links microtubules and cellulose synthase complexes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22190487.
- Also identified by DOI 10.1073/pnas.1118560109 and PMC identifier 3252916.
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Abstract
Cellulose synthase (CESA) complexes can be observed by live-cell imaging to move with trajectories that parallel the underlying cortical microtubules. Here we report that CESA interactive protein 1 (CSI1) is a microtubule-associated protein that bridges CESA complexes and cortical microtubules. Simultaneous in vivo imaging of CSI1, CESA complexes, and microtubules demonstrates that the association of CESA complexes and cortical microtubules is dependent on CSI1. CSI1 directly binds to microtubules as demonstrated by in vitro microtubule-binding assay.
Medical subject headings
- Arabidopsis
- Arabidopsis Proteins
- Carrier Proteins
- Glucosyltransferases
- Microtubules
- Multienzyme Complexes