Treatment-related change versus tumor recurrence in high-grade gliomas: a diagnostic conundrum--use of dynamic susceptibility contrast-enhanced (DSC) perfusion MRI.
review · Level V
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- Record sourced from PubMed, PMID 22194475.
- Also identified by DOI 10.2214/AJR.11.7417.
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Abstract
The purpose of this article is to address radiation necrosis, pseudoprogression, and pseudoresponse relative to high-grade gliomas and evaluate the role of conventional MRI and, in particular, dynamic susceptibility contrast-enhanced perfusion MRI in assessing such treatment-related changes from tumor recurrence. Posttreatment imaging assessment of high-grade gliomas remains challenging. Familiarity with the expected MR imaging appearances of treatment-related change and tumor recurrence will help distinguish these entities allowing appropriate management.
Medical subject headings
- Brain Neoplasms
- Glioma
- Magnetic Resonance Imaging
- Neoplasm Recurrence, Local
- Radiation Injuries