Learning to protect your genome on the fly.
editorial · Level V
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- Record sourced from PubMed, PMID 22196722.
- Also identified by DOI 10.1016/j.cell.2011.12.001 and PMC identifier 3725141.
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Abstract
Piwi-interacting RNAs (piRNAs) help defend host genomes against germline transposons. In this issue of Cell, Khurana et al. show how alterations in the piRNA-encoding loci within a single generation allow a naive fly genome to overcome the initially insurmountable challenge imposed by a newly encountered mobile element.