Metabolic connections during apoptotic cell engulfment.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22196723.
- Also identified by DOI 10.1016/j.cell.2011.12.006 and PMC identifier 3254670.
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Abstract
Billions of cells die via apoptosis every day and are swiftly removed. When a phagocyte engulfs an apoptotic cell, it essentially doubles its cellular contents, raising the question of how a phagocyte may manage the excess metabolic load. This Minireview discusses phagocyte cellular metabolism, the digestion of the ingested apoptotic cell, and the impact of these processes on engulfment.
Medical subject headings
- Apoptosis
- Phagocytes
- Phagocytosis