Additional drug resistance in Mycobacterium tuberculosis isolates from resected cavities among patients with multidrug-resistant or extensively drug-resistant pulmonary tuberculosis.
retrospective_cohort · Level III
Where this comes from
- Record sourced from PubMed, PMID 22198790.
- Also identified by DOI 10.1093/cid/cir904 and PMC identifier 3284212.
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Abstract
The pathogenesis of increasing drug resistance among patients with multidrug-resistant or extensively drug-resistant tuberculosis undergoing treatment is poorly understood. Increasing drug resistance found among Mycobacterium tuberculosis recovered from cavitary isolates compared with paired sputum isolates suggests pulmonary cavities may play a role in the development of worsening tuberculosis drug resistance.
Medical subject headings
- Antitubercular Agents
- Drug Resistance, Multiple, Bacterial
- Extensively Drug-Resistant Tuberculosis
- Lung
- Mycobacterium tuberculosis
- Sputum
- Tuberculosis, Multidrug-Resistant