Current histological diagnosis of lymphomatoid granulomatosis.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22214969.
- Also identified by DOI 10.1038/modpathol.2011.149.
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Abstract
The current histological criteria for the diagnosis of lymphomatoid granulomatosis (LYG) are reviewed and summarized. The majority of patients present with multiple bilateral nodules involving the lung. Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable numbers of CD20-positive B cells that show positivity for EBER by in situ hybridization.
Medical subject headings
- B-Lymphocytes
- Herpesvirus 4, Human
- Lung Neoplasms
- Lymphomatoid Granulomatosis
- T-Lymphocytes