Bipolar depression and treatment with antidepressants.

Goodwin, Guy M · Br J Psychiatry · 2012

editorial · Level V

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Abstract

Treatment of bipolar disorder with antidepressants tested almost exclusively in unipolar cases is common but unsupported by an appropriate body of evidence. This anomaly is highlighted by a large Taiwanese study, which implies that patients with depression difficult to treat with antidepressants are quite likely to be diagnosed subsequently with bipolar disorder.

Medical subject headings