Stem cells deployed for bone repair hijacked by T cells.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22226348.
- Also identified by DOI 10.1016/j.stem.2011.12.010.
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Abstract
Mesenchymal stem cells (MSCs) are a promising source for bone regeneration. Recently, in Nature Medicine, Liu et al. (2011) reported that host lymphocytes secrete IFN-γ and TNF-α to initiate apoptosis of transplanted MSCs and that aspirin can alleviate these effects to improve bone repair.