Abatacept and sodium thiosulfate for treatment of recalcitrant juvenile dermatomyositis complicated by ulceration and calcinosis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 22244459.
- Also identified by DOI 10.1016/j.jpeds.2011.11.057 and PMC identifier 3306811.
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Abstract
We report the successful use of abatacept and sodium thiosulfate in a patient with severe recalcitrant juvenile dermatomyositis complicated by ulcerative skin disease and progressive calcinosis. This combination therapy resulted in significant reductions in muscle and skin inflammation, decreased corticosteroid dependence, and halted the progression of calcinosis.
Medical subject headings
- Anti-Inflammatory Agents
- Antioxidants
- Calcinosis
- Chelating Agents
- Dermatomyositis
- Immunoconjugates
- Immunosuppressive Agents
- Skin Ulcer
- Thiosulfates