Critique of "Stenting versus aggressive medical therapy for intracranial arterial stenosis" by Chimowitz et al in the new England Journal of Medicine.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 22246688.
- Also identified by DOI 10.1161/STROKEAHA.111.641563.
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Abstract
Symptomatic intracranial stenoses are an important cause of stroke and have a high risk of recurrent stroke with medical therapy. The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial unexpectedly showed a higher-than-expected rate of complications with intracranial stenting and a lower-than-expected recurrence rate with medical therapy. In this commentary, the authors review possible explanations for these findings and suggest future strategies for study.
Medical subject headings
- Cerebral Arterial Diseases
- Stents
- Stroke