RIP3 finds partners in crime.
editorial · Level V
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- Record sourced from PubMed, PMID 22265396.
- Also identified by DOI 10.1016/j.cell.2011.12.020 and PMC identifier 3571655.
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Abstract
Programmed necrosis has long been recognized as a crucial component of animal development; however, the signaling pathway beyond the protein kinases RIP1 and RIP3 remains largely unknown. Sun et al. and Wang et al. now identify critical factors downstream of RIP1 and RIP3 in programmed necrosis, extending our understanding of this form of cell death.