Type B aortic dissection after the use of tadalafil.

Lameijer, Charlotte M; Tielliu, Ignace F J; van Driel, Mels F; Zeebregts, Clark J · Ann Thorac Surg · 2012

case_report · Level V

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Abstract

A 63-year-old male patient with a type B aortic dissection after the use of tadalafil, a phosphodiesterase type 5 inhibitor, is presented. The possible role of a novel predisposing factor--sexual activity combined with tadalafil--is reviewed. This report and three other cases add a new dimension to the known predisposing factors such as chronic systemic hypertension, hereditary connective tissue diseases- and congenital aortic valve diseases. However, the precise role of phosphodiesterase type 5 inhibitors in the pathophysiology of aortic dissection remains unknown.

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