PET imaging of tumor growth: not as easy as it looks.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22275505.
- Also identified by DOI 10.1158/1078-0432.CCR-11-3198 and PMC identifier 3294137.
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Abstract
Positron emission tomography can be used to image tumor proliferation when combined with appropriate labeled tracers, such as the thymidine analog [(18)F]-3'-deoxy-3'-fluorothymidine. Although thymidine kinase 1 is the principal mechanism of cell trapping, other variables, such as the cellular level of native thymidine, may need to be considered.
Medical subject headings
- Dideoxynucleosides
- Neoplasms
- Positron-Emission Tomography