Multi-scale modelling of elastic moduli of trabecular bone.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22279160.
- Also identified by DOI 10.1098/rsif.2011.0814 and PMC identifier 3367819.
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Abstract
We model trabecular bone as a nanocomposite material with hierarchical structure and predict its elastic properties at different structural scales. The analysis involves a bottom-up multi-scale approach, starting with nanoscale (mineralized collagen fibril) and moving up the scales to sub-microscale (single lamella), microscale (single trabecula) and mesoscale (trabecular bone) levels. Continuum micromechanics methods, composite materials laminate theory and finite-element methods are used in the analysis. Good agreement is found between theoretical and experimental results.
Medical subject headings
- Elasticity
- Epiphyses
- Models, Biological
- Tibia