Lipidic phase membrane protein serial femtosecond crystallography.
basic_science · Level V
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- Record sourced from PubMed, PMID 22286383.
- Also identified by DOI 10.1038/nmeth.1867 and PMC identifier 3438231.
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Abstract
X-ray free electron laser (X-FEL)-based serial femtosecond crystallography is an emerging method with potential to rapidly advance the challenging field of membrane protein structural biology. Here we recorded interpretable diffraction data from micrometer-sized lipidic sponge phase crystals of the Blastochloris viridis photosynthetic reaction center delivered into an X-FEL beam using a sponge phase micro-jet.
Medical subject headings
- Crystallography, X-Ray
- Lipid Bilayers
- Membrane Proteins