Infection-induced hematopoiesis: a zebrafish perspective.
basic_science · Level V
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- Record sourced from PubMed, PMID 22305556.
- Also identified by DOI 10.1016/j.stem.2012.01.015.
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Abstract
In response to infection, the bone marrow adjusts production of leukocyte cell types to fight off disease. In this issue of Cell Stem Cell, Hall et al. (2012) use the zebrafish model to show that nitric oxide (NO) production drives expansion of hematopoietic progenitors to produce more granulocytes.