Common signaling networks characterize leukemia-initiating cells in acute myeloid leukemia.
editorial · Level V
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- Record sourced from PubMed, PMID 22305558.
- Also identified by DOI 10.1016/j.stem.2012.01.008.
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Abstract
Identification and characterization of leukemia-initiating cells (LICs) is important to understand leukemogenesis and develop novel therapies for leukemia. In this issue of Cell Stem Cell, Gibbs et al. (2012) demonstrate that common active signaling pathways in LICs may be targeted to treat acute myeloid leukemia.