Cobalt and chromium ion release after large-diameter metal-on-metal total hip arthroplasty.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 22325959.
- Also identified by DOI 10.1016/j.arth.2011.12.016.
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Abstract
Seventy-five patients underwent unilateral metal-on-metal total hip arthroplasty using a large-diameter head. Serum levels of cobalt and chromium were determined. Significant increases in both cobalt and chromium were observed at 3 months (cobalt, 1.4 μg/L; chromium, 1.4 μg/L) compared with preoperative values (P < .001). At 1 year, the median cobalt and chromium levels were 2.3 and 2.1 μg/L, respectively, and the levels had increased significantly compared with 3 months (P < .001). There were no significant differences between levels of either metal at 1 or 2 years (cobalt, 2.3 μg/L; chromium, 1.6 μg/L). Pseudotumor occurred in 2 hips. Patients with large-diameter metal-on-metal total hip arthroplasty had higher circulating metal ion levels at 3 months and 1 year, with no additional significant increases at 2 years.
Medical subject headings
- Arthroplasty, Replacement, Hip
- Chromium
- Cobalt
- Hip Prosthesis
- Prosthesis Design
Anatomy
- hip