Rats, salt, and history.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22326213.
- Also identified by DOI 10.1016/j.cmet.2012.01.007.
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Abstract
The Dahl salt-sensitive rat is a 50-year-old enigma in hypertension research. How does salt increase blood pressure? One hypothesis put forward is the involvement of reactive oxygen species produced in the renal outer medulla. A novel rat gene-deletion model in this issue of Cell Metabolism supports this argument.