The ins and outs of inflammatory cells in atheromata.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22326216.
- Also identified by DOI 10.1016/j.cmet.2012.01.012.
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Abstract
Macrophage accumulation characterizes the formation of atherosclerotic plaques. Recent work in Nature Immunology (van Gils et al., 2012) demonstrates that the neuroimmune guidance cue netrin-1 can retain macrophages in atherosclerotic lesions, thus promoting atherosclerosis.