Cirrhosis due to chronic hepatitis E infection in a child post-bone marrow transplant.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 22341950.
- Also identified by DOI 10.1016/j.jpeds.2012.01.028.
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Abstract
Chronic hepatitis E virus (HEV) infection occurs in immunosuppressed adults. We detected HEV ribonucleic acid in serum of an adolescent patient who had undergone bone marrow transplantation and subsequently presented with persistently increased aminotransferases and histologic chronic hepatitis, and eventually developed cirrhosis. Phylogenetic analysis revealed these HEV strains were similar to swine genotype 3a, suggesting a possible zoonosis.
Medical subject headings
- Bone Marrow Transplantation
- Hepatitis E
- Immunocompromised Host
- Liver Cirrhosis
- Precursor Cell Lymphoblastic Leukemia-Lymphoma