Mitochondria in control of cell fate.

Folmes, Clifford D L; Dzeja, Petras P; Nelson, Timothy J; Terzic, Andre · Circ Res · 2012

basic_science · Level V

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Abstract

The behavior of the mitochondrial permeability transition pore has been linked to mitochondrial maturation underlying cardiomyocyte differentiation in the embryo. Mitochondrial signaling in heart development has direct implications for cardiogenesis and stem cell lineage specification.