Neuroleptic malignant syndrome: a unique association with a tricyclic antidepressant.

Baca, L; Martinelli, L · Neurology · 1990

case_report · Level V

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Abstract

We report the lst case of neuroleptic malignant syndrome occurring in a patient receiving desipramine, a tricyclic antidepressant, with no exposure to neuroleptics. Our case suggests that this syndrome may be caused by a central imbalance between norepinephrine and dopamine, and not by dopamine depletion alone.

Medical subject headings