Comment on "Rapid cancer detection by topically spraying a γ-glutamyltranspeptidase-activated fluorescent probe".

Shi, Chunmeng · Sci Transl Med · 2012

editorial · Level V

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Abstract

A recent report from Urano et al. described the development of near-infrared (NIR) probes for cancer detection using chemical bioconjugation of targeting agents. Here, I highlight an alternative strategy to develop cancer-selective NIR imaging and theranostic agents without chemical conjugation.

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