False-positive lesions mimicking breast cancer on FDG PET and PET/CT.

Adejolu, Margaret; Huo, Lei; Rohren, Eric; Santiago, Lumarie; Yang, Wei T · AJR Am J Roentgenol · 2012

case_series · Level IV

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Abstract

Incidental (18)F-FDG-avid breast lesions are commonly encountered in patients with cancer who undergo staging PET/CT. This pictorial essay discusses breast lesions that show increased FDG activity, mimicking breast cancer, with biopsy-confirmed benign diagnosis. Acute and chronic inflammation, physiologic lactation, and benign breast masses, including silicone granuloma, fat necrosis, fibroadenoma, and postsurgical changes, may show increased FDG uptake on PET/CT. These conditions can often be differentiated from malignancy by correlative imaging, including mammography, sonography, or MRI.

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