A portable and integrated nucleic acid amplification microfluidic chip for identifying bacteria.
basic_science · Level V
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- Record sourced from PubMed, PMID 22395179.
- Also identified by DOI 10.1039/c2lc40055c.
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Abstract
In this work, we developed a portable integrated microchip of loop-mediated isothermal nucleic acid amplification (LAMP). This chip, with sample-to-answer capability, could perform rapid DNA release, exponential signal amplification and naked-eye result read-out in single or multiplex format. We call it iμLAMP, namely integrated micro-LAMP, which was successfully used for point-of-care identification of bacteria.
Medical subject headings
- Bacteria
- DNA, Bacterial
- Microfluidic Analytical Techniques
- Nucleic Acid Amplification Techniques
- Point-of-Care Systems