Supersizing the mitochondrial respiratory chain.
basic_science · Level V
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- Record sourced from PubMed, PMID 22405063.
- Also identified by DOI 10.1016/j.cmet.2012.02.009.
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Abstract
The complexes of the mitochondrial respiratory chain assemble into higher-order structures called supercomplexes or respirasomes that are thought to be important in channeling electron flow and controlling ROS production. A number of recent papers identify the first protein factors necessary for supercomplex assembly and stability.