Gold nanoparticle-induced formation of artificial protein capsids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22414047.
- Also identified by DOI 10.1021/nl3002155.
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Abstract
Gold nanoparticles are generally considered to be biologically inactive. However, in this study we show that the addition of 1.4 nm diameter gold nanoparticle induces the remodeling of the ring-shaped protein TRAP into a hollow, capsid-like configuration. This structural remodeling is dependent upon the presence of cysteine residues on the TRAP surface as well as the specific type of gold nanoparticle. The results reveal an apparent novel catalytic role of gold nanoparticles.
Medical subject headings
- Capsid
- Gold
- Metal Nanoparticles