Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets.

Um, Eujin; Rha, Eugene; Choi, Su-Lim; Lee, Seung-Goo; Park, Je-Kyun · Lab Chip · 2012

basic_science · Level V

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Abstract

We constructed a mesh-grid integrated microwell array which enables easy trapping and consistent addition of droplets. The grid acts as a microchannel structure to guide droplets into the microwells underneath, and also provides open access for additional manipulation in a high-throughput manner. Each droplet in the array forms a stable environment of pico-litre volume to implement a single-cell-based assay.

Medical subject headings