Quantum-dot-tagged reduced graphene oxide nanocomposites for bright fluorescence bioimaging and photothermal therapy monitored in situ.

Hu, Shang-Hsiu; Chen, Yu-Wei; Hung, Wen-Ting; Chen, I-Wei; Chen, San-Yuan · Adv Mater · 2012

basic_science · Level V

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Abstract

Quantum-dot-tagged reduced graphene oxide (QD-rGO) nanocomposites (left) internalized into targeted tumor cells display bright fluorescence from the QDs (right); by absorbing NIR radiation incident on the rGO and converting it into heat, they also cause simultaneous cell death and fluorescence reduction (bottom). The nanocomposite is thus capable of tumor imaging, photothermal therapy and in situ monitoring of treatment in progress.

Medical subject headings