Antibody-based immunotherapy of cancer.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22424219.
- Also identified by DOI 10.1016/j.cell.2012.02.034 and PMC identifier 3310896.
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Abstract
By targeting surface antigens expressed on tumor cells, monoclonal antibodies have demonstrated efficacy as cancer therapeutics. Recent successful antibody-based strategies have focused on enhancing antitumor immune responses by targeting immune cells, irrespective of tumor antigens. We discuss these innovative strategies and propose how they will impact the future of antibody-based cancer therapy.
Medical subject headings
- Antibodies, Monoclonal
- Cancer Vaccines
- Neoplasms