Simple localization of nanofiber scaffolds via SU-8 photoresist and their use for parallel 3D cellular assays.

Jiang, Lei; Zhang, Min; Li, Jiaxing; Wen, Weijia; Qin, Jianhua · Adv Mater · 2012

basic_science · Level V

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Abstract

A simple, new approach to localizing electrospun nanofiber scaffolds simply by direct writing of SU-8 photoresist followed by UV polymerization is presented. This method allows 3D cell culture arrays to be produced and it can be integrated with microfluidic devices easily to enable low-cost high-throughput cellular assays within an addressable 3D environment, which is attractive for use in drug screening, stem cell research, tissue engineering, and regenerative medicine.

Medical subject headings