Approach to and treatment of goiters.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22443980.
- Also identified by DOI 10.1016/j.mcna.2012.01.010.
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Abstract
The main causes of simple diffuse goiter (SDG) and multinodular goiter (MNG) are iodine deficiency, increase in serum thyroid-stimulating hormone (TSH) level, natural goitrogens, smoking, chronic malnutrition, and lack of selenium, iron, and zinc. Increasing evidence suggests that heredity is equally important. Treatment of SDG and MNG still focuses on L-thyroxine-suppressive therapy surgery. Radioiodine alone or preceded by recombinant human TSH stimulation is widely used in Europe and other countries. Each of these therapeutic options has advantages and disadvantages, with acute and long-term side effects.
Medical subject headings
- Goiter
- Iodine Radioisotopes
- Thyroidectomy
- Thyrotropin
- Thyroxine