Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22447724.
- Also identified by DOI 10.1002/adma.201103832.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Multi-walled carbon nanotubes (MWCNTs) promote calcification during hydroxyapatite (HA) formation by osteoblasts. Primary cultured osteoblasts are incubated with MWCNTs or carbon black. After culture for 3 weeks, the degree of calcification is very high in the 50 μg mL(-1) MWCNT group. Transmission electron microscopy shows needle-like crystals around the MWCNTs, and diffraction patterns reveal that the peak of the crystals almost coincides with the known peak of HA.
Medical subject headings
- Bone and Bones
- Calcification, Physiologic
- Nanotubes, Carbon
- Osteoblasts