Schizophrenia and Marfan syndrome.

Sirota, P; Frydman, M; Sirota, L · Br J Psychiatry · 1990

case_report · Level V

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Abstract

Five index patients and three of their first-degree relatives were affected both by schizophrenia and Marfan syndrome. Since the association appears statistically significant, the possibility of linkage disequilibrium between adjacent genes or a cytogenetic abnormality causing both disorders is suggested. These hypotheses are testable and hold promise in attempting to map the 'schizophrenia susceptibility gene' by the candidate-gene approach.

Medical subject headings