Pluripotent stem cell-based cancer therapy: promise and challenges.

Sharkis, Saul J; Jones, Richard J; Civin, Curt; Jang, Yoon-Young · Sci Transl Med · 2012

review · Level V

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Abstract

The development of induced pluripotent stem cell (iPSC) technology has generated enthusiasm about the therapeutic potential of these cells for treating a variety of diseases. However, the evidence that they actually will be clinically useful is limited. Here, we discuss the potential therapeutic applications of iPSCs for treating cancer and other diseases and highlight the current barriers restricting their use.

Medical subject headings