Factor V Leiden: how great is the risk of venous thromboembolism?
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 22473726.
- Also identified by DOI 10.3949/ccjm.79a.11072.
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Abstract
The factor V Leiden mutation, the most common inherited cause of thrombophilia, causes a mild hypercoagulable state. We describe a 29-year-old man, heterozygous for factor V Leiden, who developed extensive pulmonary emboli with concomitant bilateral deep venous thrombosis, likely provoked by prolonged immobility during a car trip. We then review the diagnosis, therapy, screening, and prognosis of venous thromboembolism related to factor V Leiden.
Medical subject headings
- Factor V
- Thrombophilia
- Venous Thromboembolism