Fatal rhabdomyolysis in 2 children with LPIN1 mutations.

Bergounioux, Jean; Brassier, Anais; Rambaud, Caroline; Bustarret, Olivier; Michot, Caroline; Hubert, Laurence; Arnoux, Jean Baptiste; Laquerriere, Annie et al. · J Pediatr · 2012

case_report · Level V

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Abstract

We report 2 cases of fatal rhabdomyolysis in children carrying an LPIN1 mutations preceded by similar electrocardiogram changes, including diffuse symmetrical high-amplitude T waves. Our report underlines the severity of this disease and the need for active management of episodes of rhabdomyolysis in a pediatric intensive care unit.

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