In epigenetic therapy, less is more.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 22482500.
- Also identified by DOI 10.1016/j.stem.2012.03.012.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
How DNA methylation inhibitors exert their anticancer effects in patients is not well understood. In the latest issue of Cancer Cell, Tsai et al. (2012) use low-dose drug treatment to induce persistent attenuation of tumorigenicity by targeting tumor-initiating cells.