Orchestration of metabolism by macrophages.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 22482726.
- Also identified by DOI 10.1016/j.cmet.2011.11.013.
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Abstract
Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.
Medical subject headings
- Macrophages
- Metabolic Networks and Pathways