Comparison of four local extradural anaesthetic solutions for elective caesarean section.

Howell, P; Davies, W; Wrigley, M; Tan, P; Morgan, B · Br J Anaesth · 1990

rct · Level II

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Abstract

We have examined a combination of two local anaesthetics to see if the resultant solution is superior to the agents individually. This study shows that a mixture of bupivacaine and lignocaine provided an excellent alternative to bupivacaine alone, and was superior to 2% lignocaine with adrenaline for elective Caesarean section. By reducing the dose of bupivacaine used, the combination may reduce the risk of cardiotoxicity.

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