TH2 cytokines increase kallikrein 7 expression and function in patients with atopic dermatitis.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 22521249.
- Also identified by DOI 10.1016/j.jaci.2012.03.006 and PMC identifier 3387356.
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Abstract
Here we report that Th2 cytokines increase kallikrein 7 expression and function in keratinocytes. Our finding describes a link between the Th2 environment and epidermal barrier dysfunction in atopic dermatitis.
Medical subject headings
- Dermatitis, Atopic
- Interleukin-13
- Interleukin-4
- Kallikreins
- Th2 Cells