An image analysis toolbox for high-throughput C. elegans assays.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22522656.
- Also identified by DOI 10.1038/nmeth.1984 and PMC identifier 3433711.
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Abstract
We present a toolbox for high-throughput screening of image-based Caenorhabditis elegans phenotypes. The image analysis algorithms measure morphological phenotypes in individual worms and are effective for a variety of assays and imaging systems. This WormToolbox is available through the open-source CellProfiler project and enables objective scoring of whole-worm high-throughput image-based assays of C. elegans for the study of diverse biological pathways that are relevant to human disease.
Medical subject headings
- Caenorhabditis elegans
- High-Throughput Screening Assays
- Image Processing, Computer-Assisted
- Microscopy, Fluorescence
- Pattern Recognition, Automated