Association between circulating DNA, serum (1->3)-β-D-glucan, and pulmonary fungal burden in Pneumocystis pneumonia.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 22523258.
- Also identified by DOI 10.1093/cid/cis412.
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Abstract
Circulating Pneumocystis jirovecii DNA and (1→3)-β-d-glucan determined in 70 serum samples from immunocompromised patients were compared to fungal load in bronchoalveolar lavage fluids assessed using quantitative polymerase chain reaction. Both serum biomarkers are influenced by pulmonary fungal load, which should be taken into account when diagnosing Pneumocystis infection.
Medical subject headings
- Bronchoalveolar Lavage Fluid
- Colony Count, Microbial
- DNA, Fungal
- Pneumocystis carinii
- Pneumonia, Pneumocystis
- beta-Glucans