Hierarchical formation of supramolecular transient networks in water: a modular injectable delivery system.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22528786.
- Also identified by DOI 10.1002/adma.201104072.
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Abstract
A modular one-component supramolecular transient network in water, based on poly(ethylene glycol) and end-capped with four-fold hydrogen bonding units, is reported. Due to its nonlinear structural formation, this system allows active proteins to be added to the hydrogel during formation. Once implanted in vivo it releases the protein by erosion of both the protein and polymer via dissolution.
Medical subject headings
- Drug Carriers
- Water