Electrospun TiO2 nanofiber-based cell capture assay for detecting circulating tumor cells from colorectal and gastric cancer patients.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22528884.
- Also identified by DOI 10.1002/adma.201200155.
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Abstract
A nanostructured platform that combines electrospun TiO(2) nanofibers (TiNFs)-deposited substrate and cell-capture agent realizes significant capture of circulating tumor cells (CTCs). The enhanced local topographic interactions between the horizontally packed TiNFs deposited substrates and extracellular matrix scaffolds, in addition to anti-EpCAM/EpCAM biological recognition, contributes to the significantly enhanced capture efficiency compared to flat surfaces.
Medical subject headings
- Colorectal Neoplasms
- Nanofibers
- Neoplastic Cells, Circulating
- Stomach Neoplasms
- Titanium