Near-infrared light-triggered, targeted drug delivery to cancer cells by aptamer gated nanovehicles.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22539076.
- Also identified by DOI 10.1002/adma.201104797.
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Abstract
A novel cell-targeting, near-infrared light-responsive drug delivery platform based on mesoporous silica-coated gold nanorods that are surface-functionalized with aptamer DNA is constructed. Aptamer DNA is used as both capping and targeting agent. In vitro studies show the feasibility of using this nanocarrier for targeted and noninvasive remote controlled drug delivery and photothermal therapy.
Medical subject headings
- Aptamers, Nucleotide
- Drug Carriers
- Infrared Rays
- Nanotubes